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Julian Blagg Selected Research

Cyclin-Dependent Kinase 8

11/2021Identification and characterization of the mediator kinase-dependent myometrial stem cell phosphoproteome.
2/2016Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19.

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Julian Blagg Research Topics

Disease

25Neoplasms (Cancer)
04/2021 - 03/2010
6Colorectal Neoplasms (Colorectal Cancer)
04/2017 - 01/2011
2Sarcoma (Soft Tissue Sarcoma)
04/2021 - 01/2019
2Neuroblastoma
11/2020 - 11/2011
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2020 - 10/2012
2Pain (Aches)
06/2015 - 01/2010
1Leiomyoma (Uterine Fibroids)
11/2021
1Rhabdomyosarcoma
04/2021
1Neoplasm Metastasis (Metastasis)
10/2019
1Triple Negative Breast Neoplasms
10/2019
1Ewing Sarcoma (Sarcoma, Ewing)
01/2019
1Chordoma
01/2019
1Colonic Neoplasms (Colon Cancer)
01/2018
1Melanoma (Melanoma, Malignant)
01/2018
1Aneuploidy (Aneuploid)
04/2017
1Chromosomal Instability (Chromosome Stability)
04/2017
1Mental Disorders (Mental Disorder)
01/2017
1Carcinogenesis
12/2016
1Prostatic Neoplasms (Prostate Cancer)
09/2016
1Cardiovascular Diseases (Cardiovascular Disease)
12/2015
1Urinary Incontinence
05/2011
1Rare Diseases (Rare Disease)
01/2011
1Body Weight (Weight, Body)
07/2010
1Carcinoma (Carcinomatosis)
07/2010
1Erectile Dysfunction
04/2010
1Chronic Pain
01/2010
1Thrombosis (Thrombus)
11/2007
1Venous Thrombosis (Deep-Vein Thrombosis)
11/2007
1Hemorrhage
11/2007
1Necrosis
09/2007

Drug/Important Bio-Agent (IBA)

7Phosphotransferases (Kinase)IBA
11/2021 - 11/2011
6Pharmaceutical PreparationsIBA
11/2018 - 03/2010
5Biomarkers (Surrogate Marker)IBA
10/2016 - 10/2012
3Proteins (Proteins, Gene)FDA Link
11/2021 - 01/2011
3Mediator ComplexIBA
11/2021 - 12/2015
3Aurora KinasesIBA
10/2012 - 03/2010
2Cyclin-Dependent Kinase 8IBA
11/2021 - 02/2016
2Histone DemethylasesIBA
04/2021 - 01/2017
2Transcription Factors (Transcription Factor)IBA
11/2020 - 01/2019
2BOS172722IBA
10/2019 - 01/2018
2Paclitaxel (Taxol)FDA LinkGeneric
10/2019 - 01/2012
2Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2019 - 01/2018
2sapropterin (tetrahydrobiopterin)FDA Link
06/2015 - 01/2010
1JIB-04IBA
04/2021
1Adrenergic Agents (Adrenergic Drugs)IBA
11/2020
1Temozolomide (Temodar)FDA LinkGeneric
11/2020
1CYC065IBA
11/2020
1quizartinibIBA
01/2020
1Histones (Histone)IBA
10/2019
1GSK2879552IBA
01/2019
1Brachyury protein (Brachyury)IBA
01/2019
1RoscovitineIBA
01/2018
1OligonucleotidesIBA
01/2018
1purineIBA
01/2018
1Indicators and Reagents (Reagents)IBA
10/2017
1Biological ProductsIBA
10/2017
1CCT271850IBA
04/2017
1AntibodiesIBA
04/2017
1ChromatinIBA
01/2017
1AcyltransferasesIBA
12/2016
1Androgen Receptors (Androgen Receptor)IBA
09/2016
1abirateroneIBA
09/2016
1enzalutamideIBA
09/2016
1CCT251545IBA
12/2015
1Gefitinib (Iressa)FDA Link
08/2015
1GTP Cyclohydrolase (GTP Cyclohydrolase I)IBA
06/2015
1Peptides (Polypeptides)IBA
12/2013
1Protein Kinases (Protein Kinase)IBA
12/2013
1Adenosine Triphosphate (ATP)IBA
12/2013
1benzocycloheptapyridineIBA
10/2012
1UbiquitinIBA
01/2012
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2012
1taxaneIBA
01/2012
1Taxoids (Taxanes)IBA
01/2012
1Antimitotic AgentsIBA
11/2011
1N-Myc Proto-Oncogene ProteinIBA
11/2011
13- ((4- (6- bromo- 2- (4- (4- methylpiperazin- 1- yl)phenyl)- 3H- imidazo(4,5- b)pyridin- 7- yl)piperazin- 1- yl)methyl)- 5- methylisoxazoleIBA
11/2011
15-HT2C Serotonin ReceptorIBA
05/2011
1PF 3246799IBA
05/2011
1AzepinesIBA
05/2011
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2011
1beta CateninIBA
07/2010
1Sildenafil Citrate (Viagra)FDA Link
04/2010
1Carboxypeptidase B2 (Thrombin Activatable Fibrinolysis Inhibitor)IBA
11/2007
1FibrinIBA
11/2007
1compound 21IBA
11/2007
1DiureticsIBA
09/2007
1Furosemide (Lasix)FDA LinkGeneric
09/2007

Therapy/Procedure

4Therapeutics
11/2020 - 01/2010
4Oral Administration
10/2016 - 07/2010
1Hysterectomy
11/2021
1Castration
09/2016